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Improving the Activity of Trp-Rich Antimicrobial Peptides by Arg/Lys Substitutions and Changing the Length of Cationic Residues

Antimicrobial peptides (AMPs) constitute a promising alternative for the development of new antibiotics that could potentially counteract the growing number of antibiotic-resistant bacteria. However, the AMP structure–function relationships remain unclear and detailed studies are still necessary. Th...

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Detalles Bibliográficos
Autores principales: Arias, Mauricio, Piga, Kathlyn B., Hyndman, M. Eric, Vogel, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023086/
https://www.ncbi.nlm.nih.gov/pubmed/29671805
http://dx.doi.org/10.3390/biom8020019