Autocleavage of the paracaspase MALT1 at Arg-781 attenuates NF-κB signaling and regulates the growth of activated B-cell like diffuse large B-cell lymphoma cells

MALT1 controls several receptors-mediated signaling to nuclear factor κB (NF-κB) through both its scaffold and protease function. MALT1 protease activity is shown to inactivate several negative regulators of NF-κB signaling and augment NF-κB activation ability. In this study, MALT1 was demonstrated...

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Detalles Bibliográficos
Autores principales: Wu, Chun-Hsien, Yang, Yu-Hsuan, Chen, Mei-Ru, Tsai, Ching-Hwa, Cheng, Ann-Lii, Doong, Shin-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023146/
https://www.ncbi.nlm.nih.gov/pubmed/29953499
http://dx.doi.org/10.1371/journal.pone.0199779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023146/
https://www.ncbi.nlm.nih.gov/pubmed/29953499
http://dx.doi.org/10.1371/journal.pone.0199779

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