Uncovering the fine print of the CreER(T2)-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene

FAcilitates Chromatin Transcription (FACT) is a complex of SSRP1 and SPT16 that is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT has been mostly studied in cell-free or single cell model systems because general FACT knockout (KO) is embryonically lethal (E3...

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Detalles Bibliográficos
Autores principales: Sandlesh, Poorva, Juang, Thierry, Safina, Alfiya, Higgins, Michael J., Gurova, Katerina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023160/
https://www.ncbi.nlm.nih.gov/pubmed/29953487
http://dx.doi.org/10.1371/journal.pone.0199785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023160/
https://www.ncbi.nlm.nih.gov/pubmed/29953487
http://dx.doi.org/10.1371/journal.pone.0199785

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