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Uncovering the fine print of the CreER(T2)-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene
FAcilitates Chromatin Transcription (FACT) is a complex of SSRP1 and SPT16 that is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT has been mostly studied in cell-free or single cell model systems because general FACT knockout (KO) is embryonically lethal (E3...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023160/ https://www.ncbi.nlm.nih.gov/pubmed/29953487 http://dx.doi.org/10.1371/journal.pone.0199785 |