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Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

In response to iron deficiency, the budding yeast Saccharomyces cerevisiae undergoes a metabolic remodeling in order to optimize iron utilization. The tandem zinc finger (TZF)-containing protein Cth2 plays a critical role in this adaptation by binding and promoting the degradation of multiple mRNAs...

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Detalles Bibliográficos
Autores principales: Ramos-Alonso, Lucía, Romero, Antonia María, Soler, Maria Àngel, Perea-García, Ana, Alepuz, Paula, Puig, Sergi, Martínez-Pastor, María Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023232/
https://www.ncbi.nlm.nih.gov/pubmed/29912874
http://dx.doi.org/10.1371/journal.pgen.1007476