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Structural modification of the tripeptide KPV by reductive “glycoalkylation” of the lysine residue

Peptides that exhibit enzymatic or hormonal activities are regulatory factors and desirable therapeutic drugs because of their high target specificity and minimal side effects. Unfortunately, these drugs are susceptible to enzymatic degradation, leading to their rapid elimination and thereby demandi...

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Detalles Bibliográficos
Autores principales: Songok, Abigael C., Panta, Pradip, Doerrler, William T., Macnaughtan, Megan A., Taylor, Carol M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023233/
https://www.ncbi.nlm.nih.gov/pubmed/29953505
http://dx.doi.org/10.1371/journal.pone.0199686