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Structural modification of the tripeptide KPV by reductive “glycoalkylation” of the lysine residue
Peptides that exhibit enzymatic or hormonal activities are regulatory factors and desirable therapeutic drugs because of their high target specificity and minimal side effects. Unfortunately, these drugs are susceptible to enzymatic degradation, leading to their rapid elimination and thereby demandi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023233/ https://www.ncbi.nlm.nih.gov/pubmed/29953505 http://dx.doi.org/10.1371/journal.pone.0199686 |