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A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products

The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus monkey rhadinovirus (RRV), a gamma-2 herpesvir...

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Detalles Bibliográficos
Autores principales: Shin, Young C., Bischof, Georg F., Lauer, William A., Gonzalez-Nieto, Lucas, Rakasz, Eva G., Hendricks, Gregory M., Watkins, David I., Martins, Mauricio A., Desrosiers, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023237/
https://www.ncbi.nlm.nih.gov/pubmed/29912986
http://dx.doi.org/10.1371/journal.ppat.1007143