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A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products
The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus monkey rhadinovirus (RRV), a gamma-2 herpesvir...
Autores principales: | Shin, Young C., Bischof, Georg F., Lauer, William A., Gonzalez-Nieto, Lucas, Rakasz, Eva G., Hendricks, Gregory M., Watkins, David I., Martins, Mauricio A., Desrosiers, Ronald C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023237/ https://www.ncbi.nlm.nih.gov/pubmed/29912986 http://dx.doi.org/10.1371/journal.ppat.1007143 |
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