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Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera
While infectious agents have typical host preferences, the noninvasive enteric bacterium Vibrio cholerae is remarkable for its ability to survive in many environments, yet cause diarrheal disease (cholera) only in humans. One key V. cholerae virulence factor is its neuraminidase (VcN), which release...
Autores principales: | Alisson-Silva, Frederico, Liu, Janet Z., Diaz, Sandra L., Deng, Lingquan, Gareau, Mélanie G., Marchelletta, Ronald, Chen, Xi, Nizet, Victor, Varki, Nissi, Barrett, Kim E., Varki, Ajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023241/ https://www.ncbi.nlm.nih.gov/pubmed/29912959 http://dx.doi.org/10.1371/journal.ppat.1007133 |
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