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Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans

Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we identified and characterized the function of Mon1, an ortholog of Saccharomyces cerevisiae Mon1, in a human fungal pathogen...

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Detalles Bibliográficos
Autores principales: Son, Ye-Eun, Jung, Won-Hee, Oh, Sang-Hun, Kwak, Jin-Hwan, Cardenas, Maria E., Park, Hee-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023253/
https://www.ncbi.nlm.nih.gov/pubmed/29963312
http://dx.doi.org/10.1080/12298093.2018.1468053