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Ten Years’ Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics

The seminal paper on the CYP2D6 Activity Score (AS) was first published ten years ago and, since its introduction in 2008, it has been widely accepted in the field of pharmacogenetics. This scoring system facilitates the translation of highly complex CYP2D6 diplotype data into a patient’s phenotype...

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Detalles Bibliográficos
Autores principales: Gaedigk, Andrea, Dinh, Jean C., Jeong, Hyunyoung, Prasad, Bhagwat, Leeder, J. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023391/
https://www.ncbi.nlm.nih.gov/pubmed/29673183
http://dx.doi.org/10.3390/jpm8020015