Cargando…
Ten Years’ Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics
The seminal paper on the CYP2D6 Activity Score (AS) was first published ten years ago and, since its introduction in 2008, it has been widely accepted in the field of pharmacogenetics. This scoring system facilitates the translation of highly complex CYP2D6 diplotype data into a patient’s phenotype...
Autores principales: | Gaedigk, Andrea, Dinh, Jean C., Jeong, Hyunyoung, Prasad, Bhagwat, Leeder, J. Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023391/ https://www.ncbi.nlm.nih.gov/pubmed/29673183 http://dx.doi.org/10.3390/jpm8020015 |
Ejemplares similares
-
Prediction of CYP2D6 phenotype from genotype across world populations
por: Gaedigk, Andrea, et al.
Publicado: (2017) -
CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6(*)15 and (*)35 Genotyping
por: Riffel, Amanda K., et al.
Publicado: (2016) -
Long-Distance Phasing of a Tentative “Enhancer” Single-Nucleotide Polymorphism With CYP2D6 Star Allele Definitions
por: Boone, Erin C., et al.
Publicado: (2020) -
A longitudinal study of cytochrome P450 2D6 (CYP2D6) activity during adolescence
por: Leeder, J. Steven, et al.
Publicado: (2022) -
Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants
por: Gaedigk, Andrea, et al.
Publicado: (2010)