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Direct Reprograming to Regenerate Myocardium and Repair Its Pacemaker and Conduction System

The regenerative medicine field has been revolutionized by the direct conversion of one cell type to another by ectopic expression of lineage-specific transcription factors. The direct reprogramming of fibroblasts to induced cardiac myocytes (iCMs) by core cardiac transcription factors (Gata4, Mef2c...

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Detalles Bibliográficos
Autores principales: Adepu, Saritha, Oosterwerff, Erik F. J., Christoffels, Vincent M., Boink, Gerard J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023490/
https://www.ncbi.nlm.nih.gov/pubmed/29867004
http://dx.doi.org/10.3390/medicines5020048