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Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases
The heat shock response involved in protein misfolding is linked to the formation of toxic immunogenic proteins with heat shock proteins (HSP) as regulators of amyloid beta aggregation. The defective amyloid beta trafficking between different intracellular compartments is now relevant to HSPs and au...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023501/ https://www.ncbi.nlm.nih.gov/pubmed/29783682 http://dx.doi.org/10.3390/diseases6020039 |