Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations

Oncogenic epidermal growth factor receptors (EGFRs) can recruit key effectors in diverse cellular processes to propagate oncogenic signals. Targeted and combinational therapeutic strategies have been successfully applied for treating EGFR-driven cancers. However, a main challenge in EGFR therapies i...

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Detalles Bibliográficos
Autores principales: Jiang, Jingrui, Protopopov, Alexei, Sun, Ruobai, Lyle, Stephen, Russell, Meaghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023530/
https://www.ncbi.nlm.nih.gov/pubmed/29642553
http://dx.doi.org/10.3390/jpm8020013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023530/
https://www.ncbi.nlm.nih.gov/pubmed/29642553
http://dx.doi.org/10.3390/jpm8020013

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