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Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches. The mechanisms that generate these distinct patterns of progeny are p...

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Detalles Bibliográficos
Autores principales: McKinley, Kara L, Stuurman, Nico, Royer, Loic A, Schartner, Christoph, Castillo-Azofeifa, David, Delling, Markus, Klein, Ophir D, Vale, Ronald D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023609/
https://www.ncbi.nlm.nih.gov/pubmed/29897330
http://dx.doi.org/10.7554/eLife.36739