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Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration

Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of pitx2 expression occurs at the onset of gastrulation in several species, indicating a possible earlier role that remains relatively unexplored. Here we show that in zebrafis...

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Detalles Bibliográficos
Autores principales: Collins, Michelle M, Maischein, Hans-Martin, Dufourcq, Pascale, Charpentier, Marine, Blader, Patrick, Stainier, Didier YR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023614/
https://www.ncbi.nlm.nih.gov/pubmed/29952749
http://dx.doi.org/10.7554/eLife.34880