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Establishing the Transient Mass Balance of Thrombosis: From Tissue Factor to Thrombin to Fibrin Under Venous Flow
OBJECTIVE—: We investigated the coregulation of thrombin and fibrin as blood flows over a procoagulant surface. APPROACH AND RESULTS—: Using microfluidic perfusion of factor XIIa-inhibited human whole blood (200 s(−1) wall shear rate) over a 250-μm long patch of collagen/TF (tissue factor; ≈1 molecu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023760/ https://www.ncbi.nlm.nih.gov/pubmed/29724819 http://dx.doi.org/10.1161/ATVBAHA.118.310906 |