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RNA Aptamers Rescue Mitochondrial Dysfunction in a Yeast Model of Huntington’s Disease

Huntington’s disease (HD) is associated with the misfolding and aggregation of mutant huntingtin harboring an elongated polyglutamine stretch at its N terminus. A distinguishing pathological hallmark of HD is mitochondrial dysfunction. Any strategy that can restore the integrity of the mitochondrial...

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Detalles Bibliográficos
Autores principales:	Patel, Kinjal A., Chaudhary, Rajeev K., Roy, Ipsita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023792/ https://www.ncbi.nlm.nih.gov/pubmed/30195782 http://dx.doi.org/10.1016/j.omtn.2018.04.010

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