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MicroRNA-125b Promotes Hepatic Stellate Cell Activation and Liver Fibrosis by Activating RhoA Signaling

miR-125b is frequently dysregulated in different diseases. Activation of hepatic stellate cells (HSCs) is a critical event during liver fibrogenesis. However, the function and its underlying mechanism of miR-125b in HSC activation and liver fibrosis are still unknown. Here, we showed that miR-125b w...

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Detalles Bibliográficos
Autores principales: You, Kai, Li, Song-Yang, Gong, Jiao, Fang, Jian-Hong, Zhang, Chong, Zhang, Min, Yuan, Yunfei, Yang, Jine, Zhuang, Shi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023793/
https://www.ncbi.nlm.nih.gov/pubmed/30195793
http://dx.doi.org/10.1016/j.omtn.2018.04.016