GTP-binding facilitates EB1 recruitment onto microtubules by relieving its auto-inhibition

Microtubule plus end-binding protein, EB1 is a key regulator of microtubule dynamics. Auto-inhibitory interaction in EB1 has previously been shown to inhibit its ability to bind to microtubules and regulate microtubule dynamics. However, the factors that promote its microtubule regulatory activity b...

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Detalles Bibliográficos
Autores principales: Gireesh, K. K., Shine, A., Lakshmi, R. Bhagya, Vijayan, Vinesh, Manna, Tapas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023887/
https://www.ncbi.nlm.nih.gov/pubmed/29955158
http://dx.doi.org/10.1038/s41598-018-28056-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023887/
https://www.ncbi.nlm.nih.gov/pubmed/29955158
http://dx.doi.org/10.1038/s41598-018-28056-y

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