Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta

Haematopoietic stem cells (HSCs) are generated from haemogenic endothelial (HE) cells via the formation of intra-aortic haematopoietic clusters (IAHCs) in vertebrate embryos. The molecular events controlling endothelial specification, endothelial-to-haematopoietic transition (EHT) and IAHC formation...

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Detalles Bibliográficos
Autores principales: Baron, Chloé S., Kester, Lennart, Klaus, Anna, Boisset, Jean-Charles, Thambyrajah, Roshana, Yvernogeau, Laurent, Kouskoff, Valérie, Lacaud, Georges, van Oudenaarden, Alexander, Robin, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023921/
https://www.ncbi.nlm.nih.gov/pubmed/29955049
http://dx.doi.org/10.1038/s41467-018-04893-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023921/
https://www.ncbi.nlm.nih.gov/pubmed/29955049
http://dx.doi.org/10.1038/s41467-018-04893-3

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