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Molecular basis of Tousled-Like Kinase 2 activation

Tousled-like kinases (TLKs) are required for genome stability and normal development in numerous organisms and have been implicated in breast cancer and intellectual disability. In humans, the similar TLK1 and TLK2 interact with each other and TLK activity enhances ASF1 histone binding and is inhibi...

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Detalles Bibliográficos
Autores principales: Mortuza, Gulnahar B., Hermida, Dario, Pedersen, Anna-Kathrine, Segura-Bayona, Sandra, López-Méndez, Blanca, Redondo, Pilar, Rüther, Patrick, Pozdnyakova, Irina, Garrote, Ana M., Muñoz, Inés G., Villamor-Payà, Marina, Jauset, Cristina, Olsen, Jesper V., Stracker, Travis H., Montoya, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023931/
https://www.ncbi.nlm.nih.gov/pubmed/29955062
http://dx.doi.org/10.1038/s41467-018-04941-y