Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4

Dendritic cell (DC)-based immunotherapy makes use of the DC’s ability to direct the adaptive immune response toward activation or inhibition. DCs perform this immune orchestration in part by secretion of selected cytokines. The most potent anti-inflammatory cytokine interleukin-10 (IL-10) is under t...

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Detalles Bibliográficos
Autores principales: Søndergaard, Jonas Nørskov, van Heeringen, Simon J., Looman, Maaike W. G., Tang, Chunling, Triantis, Vassilis, Louche, Pauline, Janssen-Megens, Eva M., Sieuwerts, Anieta M., Martens, John W. M., Logie, Colin, Stunnenberg, Hendrik G., Ansems, Marleen, Adema, Gosse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023963/
https://www.ncbi.nlm.nih.gov/pubmed/29988341
http://dx.doi.org/10.3389/fimmu.2018.01420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023963/
https://www.ncbi.nlm.nih.gov/pubmed/29988341
http://dx.doi.org/10.3389/fimmu.2018.01420

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