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Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4
Dendritic cell (DC)-based immunotherapy makes use of the DC’s ability to direct the adaptive immune response toward activation or inhibition. DCs perform this immune orchestration in part by secretion of selected cytokines. The most potent anti-inflammatory cytokine interleukin-10 (IL-10) is under t...
Autores principales: | Søndergaard, Jonas Nørskov, van Heeringen, Simon J., Looman, Maaike W. G., Tang, Chunling, Triantis, Vassilis, Louche, Pauline, Janssen-Megens, Eva M., Sieuwerts, Anieta M., Martens, John W. M., Logie, Colin, Stunnenberg, Hendrik G., Ansems, Marleen, Adema, Gosse J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023963/ https://www.ncbi.nlm.nih.gov/pubmed/29988341 http://dx.doi.org/10.3389/fimmu.2018.01420 |
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