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Designing miRNA-Based Synthetic Cell Classifier Circuits Using Answer Set Programming

Cell classifier circuits are synthetic biological circuits capable of distinguishing between different cell states depending on specific cellular markers and engendering a state-specific response. An example are classifiers for cancer cells that recognize whether a cell is healthy or diseased based...

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Detalles Bibliográficos
Autores principales: Becker, Katinka, Klarner, Hannes, Nowicka, Melania, Siebert, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023966/
https://www.ncbi.nlm.nih.gov/pubmed/29988359
http://dx.doi.org/10.3389/fbioe.2018.00070