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Primary Immunodeficiencies Unravel the Role of IL-2/CD25/STAT5b in Human Natural Killer Cell Maturation

Natural killer (NK) cells play a pivotal role during immunity against viruses and circumstantial evidence also indicates that they can protect the host against developing tumors. Peripheral blood NK cells comprise CD56(bright)CD16(lo/−) cells that constitutively express CD25 (IL-2Rα) and CD56(dim)CD...

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Detalles Bibliográficos
Autores principales: Caldirola, María Soledad, Rodríguez Broggi, María Guadalupe, Gaillard, María Isabel, Bezrodnik, Liliana, Zwirner, Norberto Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023967/
https://www.ncbi.nlm.nih.gov/pubmed/29988287
http://dx.doi.org/10.3389/fimmu.2018.01429