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Diverse Impacts of HIV Latency-Reversing Agents on CD8+ T-Cell Function: Implications for HIV Cure

Antiretroviral therapy regimens durably suppress HIV replication, but do not cure infection. This is partially attributable to the persistence of long-lived pools of resting CD4+ T-cells harboring latent replication-competent virus. Substantial clinical and pre-clinical research is currently being d...

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Detalles Bibliográficos
Autores principales: Clutton, Genevieve Tyndale, Jones, R. Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023971/
https://www.ncbi.nlm.nih.gov/pubmed/29988382
http://dx.doi.org/10.3389/fimmu.2018.01452