The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health

SLC7A5, known as LAT1, belongs to the APC superfamily and forms a heterodimeric amino acid transporter interacting with the glycoprotein CD98 (SLC3A2) through a conserved disulfide. The complex is responsible for uptake of essential amino acids in crucial body districts such as placenta and blood br...

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Detalles Bibliográficos
Autores principales: Scalise, Mariafrancesca, Galluccio, Michele, Console, Lara, Pochini, Lorena, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023973/
https://www.ncbi.nlm.nih.gov/pubmed/29988369
http://dx.doi.org/10.3389/fchem.2018.00243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023973/
https://www.ncbi.nlm.nih.gov/pubmed/29988369
http://dx.doi.org/10.3389/fchem.2018.00243

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