The Initial Response of a Eukaryotic Replisome to DNA Damage

The replisome must overcome DNA damage to ensure complete chromosome replication. Here, we describe the earliest events in this process by reconstituting collisions between a eukaryotic replisome, assembled with purified proteins, and DNA damage. Lagging-strand lesions are bypassed without delay, le...

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Detalles Bibliográficos
Autores principales: Taylor, Martin R.G., Yeeles, Joseph T.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024075/
https://www.ncbi.nlm.nih.gov/pubmed/29944888
http://dx.doi.org/10.1016/j.molcel.2018.04.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024075/
https://www.ncbi.nlm.nih.gov/pubmed/29944888
http://dx.doi.org/10.1016/j.molcel.2018.04.022

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