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The Initial Response of a Eukaryotic Replisome to DNA Damage
The replisome must overcome DNA damage to ensure complete chromosome replication. Here, we describe the earliest events in this process by reconstituting collisions between a eukaryotic replisome, assembled with purified proteins, and DNA damage. Lagging-strand lesions are bypassed without delay, le...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024075/ https://www.ncbi.nlm.nih.gov/pubmed/29944888 http://dx.doi.org/10.1016/j.molcel.2018.04.022 |