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Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis

Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection. Matrix metalloproteinase-1 plays a crucial role in the immunopathology of TB, causing breakdown of type I collagen and cavitation, but this...

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Detalles Bibliográficos
Autores principales: Brilha, Sara, Chong, Deborah L. W., Khawaja, Akif A., Ong, Catherine W. M., Guppy, Naomi J., Porter, Joanna C., Friedland, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024194/
https://www.ncbi.nlm.nih.gov/pubmed/29988449
http://dx.doi.org/10.3389/fimmu.2018.01348