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Antiviral Effects of Clinically-Relevant Interferon-α and Ribavirin Regimens against Dengue Virus in the Hollow Fiber Infection Model (HFIM)

Dengue virus (DENV) is the most prevalent mosquito-borne viral illness in humans. Currently, there are no therapeutic agents available to prevent or treat DENV infections. Our objective was to fill this unmet medical need by evaluating the antiviral activity of interferon-α (IFN) and ribavirin (RBV)...

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Detalles Bibliográficos
Autores principales: Pires de Mello, Camilly P., Drusano, George L., Rodriquez, Jaime L., Kaushik, Ajeet, Brown, Ashley N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024321/
https://www.ncbi.nlm.nih.gov/pubmed/29890736
http://dx.doi.org/10.3390/v10060317