Cargando…
Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk
A number of epidemiological studies have suggested that diets rich in whole grains are linked to lower cardiovascular disease (CVD) risk and mortality. Quinoa, a pseudo-cereal, is included in the “whole grain” category but the effects of quinoa consumption in humans is not widely studied. Our aim wa...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024323/ https://www.ncbi.nlm.nih.gov/pubmed/29914146 http://dx.doi.org/10.3390/nu10060777 |
_version_ | 1783336038557548544 |
---|---|
author | Li, Liangkui Lietz, Georg Bal, Wendy Watson, Anthony Morfey, Ben Seal, Chris |
author_facet | Li, Liangkui Lietz, Georg Bal, Wendy Watson, Anthony Morfey, Ben Seal, Chris |
author_sort | Li, Liangkui |
collection | PubMed |
description | A number of epidemiological studies have suggested that diets rich in whole grains are linked to lower cardiovascular disease (CVD) risk and mortality. Quinoa, a pseudo-cereal, is included in the “whole grain” category but the effects of quinoa consumption in humans is not widely studied. Our aim was to undertake a dietary intervention study to investigate the effects of daily consumption of quinoa-enriched bread (providing 20 g quinoa flour) on CVD risk markers compared with a 100% refined wheat bread control. Thirty-seven healthy overweight men (35–70 years, body mass index >25 kg/m(2)) completed a 4-week cross-over intervention, separated by a 4-week washout period. Fasting blood samples were collected at the beginning and end of each intervention period. Continuous glucose monitoring was undertaken at the end of each intervention period. After 4 weeks of intervention, blood glucose and low density lipoprotein (LDL) cholesterol were significantly lower than baseline in both groups but there was no difference between quinoa and control. Anthropometric measures and other blood metabolites were not different between the two treatments. The cumulative area under the blood glucose curve for the last 4 days of the quinoa intervention tended to be lower than the first 4 days of wash-out (p = 0.054), and was significantly lower than the corresponding period of the wheat treatment (p = 0.039). In conclusion, daily consumption of quinoa in this short-term intervention appears to modify glucose response, but has minimal effects on other CVD risk biomarkers. |
format | Online Article Text |
id | pubmed-6024323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60243232018-07-08 Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk Li, Liangkui Lietz, Georg Bal, Wendy Watson, Anthony Morfey, Ben Seal, Chris Nutrients Article A number of epidemiological studies have suggested that diets rich in whole grains are linked to lower cardiovascular disease (CVD) risk and mortality. Quinoa, a pseudo-cereal, is included in the “whole grain” category but the effects of quinoa consumption in humans is not widely studied. Our aim was to undertake a dietary intervention study to investigate the effects of daily consumption of quinoa-enriched bread (providing 20 g quinoa flour) on CVD risk markers compared with a 100% refined wheat bread control. Thirty-seven healthy overweight men (35–70 years, body mass index >25 kg/m(2)) completed a 4-week cross-over intervention, separated by a 4-week washout period. Fasting blood samples were collected at the beginning and end of each intervention period. Continuous glucose monitoring was undertaken at the end of each intervention period. After 4 weeks of intervention, blood glucose and low density lipoprotein (LDL) cholesterol were significantly lower than baseline in both groups but there was no difference between quinoa and control. Anthropometric measures and other blood metabolites were not different between the two treatments. The cumulative area under the blood glucose curve for the last 4 days of the quinoa intervention tended to be lower than the first 4 days of wash-out (p = 0.054), and was significantly lower than the corresponding period of the wheat treatment (p = 0.039). In conclusion, daily consumption of quinoa in this short-term intervention appears to modify glucose response, but has minimal effects on other CVD risk biomarkers. MDPI 2018-06-16 /pmc/articles/PMC6024323/ /pubmed/29914146 http://dx.doi.org/10.3390/nu10060777 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Liangkui Lietz, Georg Bal, Wendy Watson, Anthony Morfey, Ben Seal, Chris Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk |
title | Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk |
title_full | Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk |
title_fullStr | Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk |
title_full_unstemmed | Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk |
title_short | Effects of Quinoa (Chenopodium quinoa Willd.) Consumption on Markers of CVD Risk |
title_sort | effects of quinoa (chenopodium quinoa willd.) consumption on markers of cvd risk |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024323/ https://www.ncbi.nlm.nih.gov/pubmed/29914146 http://dx.doi.org/10.3390/nu10060777 |
work_keys_str_mv | AT liliangkui effectsofquinoachenopodiumquinoawilldconsumptiononmarkersofcvdrisk AT lietzgeorg effectsofquinoachenopodiumquinoawilldconsumptiononmarkersofcvdrisk AT balwendy effectsofquinoachenopodiumquinoawilldconsumptiononmarkersofcvdrisk AT watsonanthony effectsofquinoachenopodiumquinoawilldconsumptiononmarkersofcvdrisk AT morfeyben effectsofquinoachenopodiumquinoawilldconsumptiononmarkersofcvdrisk AT sealchris effectsofquinoachenopodiumquinoawilldconsumptiononmarkersofcvdrisk |