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Human Metapneumovirus Small Hydrophobic Protein Inhibits Interferon Induction in Plasmacytoid Dendritic Cells

Human metapneumovirus (hMPV), a leading cause of respiratory tract infections in infants, encodes a small hydrophobic (SH) protein of unknown function. Here we show that infection of plasmacytoid dendritic cells (pDCs) with a recombinant virus lacking SH expression (rhMPV-ΔSH) enhanced the secretion...

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Detalles Bibliográficos
Autores principales: Bao, Xiaoyong, Kolli, Deepthi, Esham, Dana, Velayutham, Thangam S., Casola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024365/
https://www.ncbi.nlm.nih.gov/pubmed/29789500
http://dx.doi.org/10.3390/v10060278