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Loop Replacement Enhances the Ancestral Antibacterial Function of a Bifunctional Scorpion Toxin
On the basis of the evolutionary relationship between scorpion toxins targeting K(+) channels (KTxs) and antibacterial defensins (Zhu S., Peigneur S., Gao B., Umetsu Y., Ohki S., Tytgat J. Experimental conversion of a defensin into a neurotoxin: Implications for origin of toxic function. Mol. Biol....
Autores principales: | Zhang, Shangfei, Gao, Bin, Wang, Xueli, Zhu, Shunyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024585/ https://www.ncbi.nlm.nih.gov/pubmed/29867003 http://dx.doi.org/10.3390/toxins10060227 |
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