Cargando…

Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins

Ribosome-inactivating proteins (RIPs) are potent toxins that inactivate ribosomes by catalytically removing a specific adenine from the α-sarcin/ricin loop (SRL) of the large rRNA. Direct assays for measuring depurination activity and indirect assays for measuring the resulting translation inhibitio...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yijun, Li, Xiao-Ping, Kahn, Jennifer N., Tumer, Nilgun E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024586/
https://www.ncbi.nlm.nih.gov/pubmed/29899209
http://dx.doi.org/10.3390/toxins10060240