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Metabolic labelling of cholesteryl glucosides in Helicobacter pylori reveals how the uptake of human lipids enhances bacterial virulence

Helicobacter pylori infects approximately half of the human population and is the main cause of various gastric diseases. This pathogen is auxotrophic for cholesterol, which it converts upon uptake to various cholesteryl α-glucoside derivatives, including cholesteryl 6′-acyl and 6′-phosphatidyl α-gl...

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Detalles Bibliográficos
Autores principales: Jan, Hau-Ming, Chen, Yi-Chi, Shih, Yu-Yin, Huang, Yu-Chen, Tu, Zhijay, Ingle, Arun B., Liu, Sheng-Wen, Wu, Ming-Shiang, Gervay-Hague, Jacquelyn, Mong, Kwok-Kong Tony, Chen, Yet-Ran, Lin, Chun-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024656/
https://www.ncbi.nlm.nih.gov/pubmed/30034762
http://dx.doi.org/10.1039/c6sc00889e