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Changes in the EV-A71 Genome through Recombination and Spontaneous Mutations: Impact on Virulence

Enterovirus 71 (EV-A71) is a major etiological agent of hand, foot and mouth disease (HFMD) that mainly affects young children less than five years old. The onset of severe HFMD is due to neurological complications bringing about acute flaccid paralysis and pulmonary oedema. In this review, we addre...

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Detalles Bibliográficos
Autores principales: Mandary, Madiiha Bibi, Poh, Chit Laa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024729/
https://www.ncbi.nlm.nih.gov/pubmed/29895721
http://dx.doi.org/10.3390/v10060320