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Changes in the EV-A71 Genome through Recombination and Spontaneous Mutations: Impact on Virulence
Enterovirus 71 (EV-A71) is a major etiological agent of hand, foot and mouth disease (HFMD) that mainly affects young children less than five years old. The onset of severe HFMD is due to neurological complications bringing about acute flaccid paralysis and pulmonary oedema. In this review, we addre...
Autores principales: | Mandary, Madiiha Bibi, Poh, Chit Laa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024729/ https://www.ncbi.nlm.nih.gov/pubmed/29895721 http://dx.doi.org/10.3390/v10060320 |
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