Histone Modulation Blocks Treg-Induced Foxp3 Binding to the IL-2 Promoter of Virus-Specific CD8(+) T Cells from Feline Immunodeficiency Virus-Infected Cats

CD8(+) T cells are critical for controlling HIV infection. During the chronic phase of lentiviral infection, CD8(+) T cells lose their proliferative capacity and exhibit impaired antiviral function. This loss of CD8(+) T cell function is due, in part, to CD4(+)CD25(+) T regulatory (Treg) cell-mediat...

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Detalles Bibliográficos
Autores principales: Nag, Mukta, Wang, Yan, De Paris, Kristina, E. Fogle, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024775/
https://www.ncbi.nlm.nih.gov/pubmed/29861472
http://dx.doi.org/10.3390/v10060287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024775/
https://www.ncbi.nlm.nih.gov/pubmed/29861472
http://dx.doi.org/10.3390/v10060287

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