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Histone Modulation Blocks Treg-Induced Foxp3 Binding to the IL-2 Promoter of Virus-Specific CD8(+) T Cells from Feline Immunodeficiency Virus-Infected Cats
CD8(+) T cells are critical for controlling HIV infection. During the chronic phase of lentiviral infection, CD8(+) T cells lose their proliferative capacity and exhibit impaired antiviral function. This loss of CD8(+) T cell function is due, in part, to CD4(+)CD25(+) T regulatory (Treg) cell-mediat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024775/ https://www.ncbi.nlm.nih.gov/pubmed/29861472 http://dx.doi.org/10.3390/v10060287 |