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Myc, Oncogenic Protein Translation, and the Role of Polyamines

Deregulated protein synthesis is a common feature of cancer cells, with many oncogenic signaling pathways directly augmenting protein translation to support the biomass needs of proliferating tissues. MYC’s ability to drive oncogenesis is a consequence of its essential role as a governor linking cel...

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Detalles Bibliográficos
Autores principales: Flynn, Andrea T., Hogarty, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024823/
https://www.ncbi.nlm.nih.gov/pubmed/29799508
http://dx.doi.org/10.3390/medsci6020041