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Phage Genetic Engineering Using CRISPR–Cas Systems
Since their discovery over a decade ago, the class of prokaryotic immune systems known as CRISPR–Cas have afforded a suite of genetic tools that have revolutionized research in model organisms spanning all domains of life. CRISPR-mediated tools have also emerged for the natural targets of CRISPR–Cas...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024849/ https://www.ncbi.nlm.nih.gov/pubmed/29921752 http://dx.doi.org/10.3390/v10060335 |