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IDH2 Deficiency Aggravates Fructose-Induced NAFLD by Modulating Hepatic Fatty Acid Metabolism and Activating Inflammatory Signaling in Female Mice

Fructose is a strong risk factor for non-alcoholic fatty liver disease (NAFLD), resulting from the disruption of redox systems by excessive reactive oxygen species production in the liver cells. Of note, recent epidemiological studies indicated that women are more prone to developing metabolic syndr...

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Detalles Bibliográficos
Autores principales: Pan, Jeong Hoon, Kim, Hoe-Sung, Beane, Kaleigh Elizabeth, Montalbano, Allison Michelle, Lee, Jin Hyup, Kim, Young Jun, Kim, Jun Ho, Kong, Byungwhi Caleb, Kim, Sangyub, Park, Jeen-Woo, Shin, Eui-Cheol, Kim, Jae Kyeom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024877/
https://www.ncbi.nlm.nih.gov/pubmed/29861476
http://dx.doi.org/10.3390/nu10060679