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WIP-YAP/TAZ as A New Pro-Oncogenic Pathway in Glioma

Wild-type p53 (wtp53) is described as a tumour suppressor gene, and mutations in p53 occur in many human cancers. Indeed, in high-grade malignant glioma, numerous molecular genetics studies have established central roles of RTK-PI3K-PTEN and ARF-MDM2-p53 INK4a-RB pathways in promoting oncogenic capa...

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Detalles Bibliográficos
Autores principales: Rivas, Sergio, Antón, Inés M., Wandosell, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024887/
https://www.ncbi.nlm.nih.gov/pubmed/29890731
http://dx.doi.org/10.3390/cancers10060191