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p53-Dependent and -Independent Epithelial Integrity: Beyond miRNAs and Metabolic Fluctuations

In addition to its classical roles as a tumor suppressor, p53 has also been shown to act as a guardian of epithelial integrity by inducing the microRNAs that target transcriptional factors driving epithelial–mesenchymal transition. On the other hand, the ENCODE project demonstrated an enrichment of...

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Detalles Bibliográficos
Autores principales: Oikawa, Tsukasa, Otsuka, Yutaro, Sabe, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024951/
https://www.ncbi.nlm.nih.gov/pubmed/29799511
http://dx.doi.org/10.3390/cancers10060162