Heterologous Expression of a VioA Variant Activates Cryptic Compounds in a Marine-Derived Brevibacterium Strain

A new 14-membered homodimeric macrodiolide, brevidiolide (3), along with four known aromatic compounds (1, 2, 4 and 5) were obtained by heterologous expression of the recombinant plasmid pWLI823 expressing the G231L variant of VioA in the marine-derived Brevibacterium sp. 7002-073. The structures of...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Hou, Lukuan, Hou, Jing, Zhang, Yongyu, Li, Huayue, Li, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024985/
https://www.ncbi.nlm.nih.gov/pubmed/29865236
http://dx.doi.org/10.3390/md16060191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024985/
https://www.ncbi.nlm.nih.gov/pubmed/29865236
http://dx.doi.org/10.3390/md16060191

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