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Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin
The mechanism of intercellular transmission of pathological agents in neurodegenerative diseases has received much recent attention. Huntington’s disease (HD) is caused by a monogenic mutation in the gene encoding Huntingtin (HTT). Mutant HTT (mHTT) harbors a CAG repeat extension which encodes an ab...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025013/ https://www.ncbi.nlm.nih.gov/pubmed/29904030 http://dx.doi.org/10.3390/cells7060059 |