Clinical Relevant Polymorphisms Affecting Clopidogrel Pharmacokinetics and Pharmacodynamics: Insights from the Puerto Rico Newborn Screening Program

Background: Variations in several clopidogrel-pharmacogenes have been linked to clopidogrel response variability and clinical outcomes. We aimed to determine the frequency distribution of major polymorphisms on CYP2C19, PON1, ABCB1 and P2RY12 pharmacogenes in Puerto Ricans. Methods: This was a cross...

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Detalles Bibliográficos
Autores principales: Hernandez-Suarez, Dagmar F., Tomassini-Fernandini, Jonnalie C., Cuevas, Angelica, Rosario-Berrios, Anyelis N., Nuñez-Medina, Héctor J., Padilla-Arroyo, Dariana, Rivera, Nannette, Liriano, Jennifer, Vega-Roman, Rocio K., Renta, Jessicca Y., Melin, Kyle, Duconge, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025039/
https://www.ncbi.nlm.nih.gov/pubmed/29848980
http://dx.doi.org/10.3390/ijerph15061115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025039/
https://www.ncbi.nlm.nih.gov/pubmed/29848980
http://dx.doi.org/10.3390/ijerph15061115

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